Staff Scientist - Tumor Immunology

City of Hope

Duarte, CA

Job posting number: #7261420 (Ref:10026834)

Posted: July 10, 2024

Salary / Pay Rate: $38.67 - $123.37 / hour

Application Deadline: Open Until Filled

Job Description

Join the forefront of groundbreaking research at theBeckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.

The laboratory of Dr. Heather McGee, MD, PhD, Assistant Professor in the Departments of Radiation Oncology and Immuno-Oncology, is seeking to hire a Staff Scientist with experience in immunology, tumor immunology and/or innate immunity. Dr. McGee leads an exciting and dynamic research group at the forefront of studies on the immune response to radiation.

The focus of the lab is to understand how radiation activates tissue resident immune cells in various tumor microenvironments. Their goals are to identify key molecular and immunologic pathways activated by radiation that can be targeted to enhance anti-tumor immunity and/or minimize normal tissue toxicity for gastrointestinal (GI) malignancies. In addition, we have discovered a novel immune-mediated mechanism that contributes to the development of early-onset colorectal cancer and are investigating the epigenetic and transcriptional regulation of this pathway. This is an outstanding opportunity for a very motivated and ambitious scientist to thrive and obtain first-author publications and grants that will allow him or her to become an independent Principal Investigator in the future.

For more information on Dr. McGee’s research please visit here.

As a successful candidate, you will:

· Devise, plan, and contribute original ideas to basic science and translational projects in one or more of the following four areas:

o 1) immune response to radiation in the liver tumor microenvironment

o 2) immune determinants of early-onset colorectal cancer

o 3) radiation-induced natural killer cell (NK cell) activation

o 4) radiation-induced cell death pathways in GI cancers.

· Collect data for figures to be used for lab meetings and grant applications.

· Prepare manuscripts for publication with Dr. McGee.

· Work in close collaboration with other team members and both internal and external collaborators.

· Train and supervise junior scientists in the lab.

· The Staff Scientist must possess, at a minimum, the U.S. equivalent Bachelor’s or Master’s degree in an appropriate discipline, and will often have a Ph.D. or other doctoral level degree.

· Experience in tumor immunology and flow cytometry.

· Evidence of scientific rigor and excellence as documented by first author high-impact peer-reviewed publications.

· Previous experience working with animal models (transgenic and knock-in reporter mice).

· Strong team player with excellent communication skills and fluency in English (both spoken and written).

Preferred qualifications:

· Priority consideration will be given to candidates who possess a Ph.D. and have at least 3 years of experience.

City of Hope is an equal opportunity employer. To learn more about our commitment to diversity, equity and inclusion, please click here.

To learn more about our Comprehensive Benefits, pleaseCLICK HERE.

Salary / Pay Rate Information:
Pay Rate: $38.67 - $123.37 / hour

The estimated pay scale represents the typical [salary/hourly] range City of Hope reasonably expects to pay for this position, with offers determined based on several factors which may include, but not be limited to, the candidate’s experience, expertise, skills, education, job scope, training, internal equity, geography/market, etc. This pay scale is subject to change from time to time.

City of Hope is a community of people characterized by our diversity of thought, background and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. The innovation that our diversity produces in the areas of research, treatment, philanthropy and education has made us national leaders in this fight. Our unique and diverse workforce provides us the ability to understand our patients' needs, deliver compassionate care and continue the quest for a cure for life-threatening diseases. At City of Hope, diversity and inclusion is a core value at the heart of our mission. We strive to create an inclusive workplace environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally. Each day brings an opportunity to strengthen our work, leverage our different perspectives and improve our patients’ experiences by learning from others. Diversity and inclusion is about much more than policies and campaigns. It is an integral part of who we are as an institution, how we operate and how we see our future.

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More Info

Job posting number:#7261420 (Ref:10026834)
Application Deadline:Open Until Filled
Employer Location:City of Hope
United States
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