Summary

The lab is looking for highly motivated candidates to join a team of physician scientists, scientists, postdoctoral fellows, technicians and graduate students to support research on cancer immunotherapy using CAR T cells. The technician will provide responsible technical assistance in support of research projects by completing assignments requiring a basic knowledge of fundamental techniques and practices related to basic and translational research in cellular immunotherapy of cancer. The technician will work under supervision in accordance with general plans approved by the principal investigator.

Job Duties

• Prepares and conducts laboratory research experiments.
• Collects, compiles, and analyzes data.
• Conducts literature searches and summarizes information in an appropriate format for a particular study.
• Documents results of experiments.
• Selects, evaluates, and applies techniques used in routine research.
• Orders laboratory supplies and equipment.
• Conducts aseptic cell culture for maintenance and propagation of tumor lines.
• Handles and processes peripheral blood and immune cells after appropriate training per institutional guidelines.
• Works on production, maintenance, and cryopreservation of CAR T cells.
• Conducts genetic engineering techniques that includes PCR, cloning, retroviral transduction, and library preparations.
• Works on flow cytometry alongside immunological assays that includes multiplex assays, ELISA, ELISPOT and Western blotting.
• Works with mouse models of cancer after appropriate training as per institutional guidelines.
• Assists in phase I clinical trial related sample receipt, handling, and documentation with appropriate training and under supervision.
• Performs immunohistochemistry and associated image analysis.
• Uses office suite, instrument interface and other softwares for data collation and analysis.
• Assists in ordering laboratory supplies with appropriate guidance from the laboratory manager/PI.
• Assists in testing of research samples and administrative tasks involved in conduct of clinical trial.
• Performs research experiments to produce reliable and precise data to support scientific investigations in cell and gene therapy applications under the supervision of principal investigator.
• Records and summarizes research data generated from experiments, prepare figures, and analyze for presentations and publications.
• Performs other job-related duties as assigned.

Minimum Qualifications

• Bachelor's degree in a Basic Science or related field. Four years of related experience may substitute for degree requirement.
• No experience required.

Preferred Qualifications

• Experience full time/part time working in research laboratory.
• Workswith animals models, retroviral/lentiviral transduction, phage library maintenance.